UniprotKB/SwissProt ID: RB3GP_MOUSE (Q80UJ7)
Gene Name: Rab3gap1
Synonyms: Kiaa0066, Rab3gap
Organism: Mus musculus (Mouse).
Function: Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Note=In neurons, it is enriched in the synaptic soluble fraction (By similarity).
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