UniprotKB/SwissProt ID: RHOC_HUMAN (P08134)
Gene Name: RHOC
Synonyms: ARH9, ARHC
Organism: Homo sapiens (Human).
Function: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Cleavage furrow. Note=Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
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