Protein Name: Rho-related GTP-binding protein RhoG
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UniprotKB/SwissProt ID: RHOG_HUMAN (P84095)
Gene Name: RHOG
Synonyms: ARHG
Organism: Homo sapiens (Human).
Function: Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential).
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | OMIM | 179505 | RAS HOMOLOG GENE FAMILY, MEMBER G; RHOG ;;RAS HOMOLOG GENE G;; ARHG |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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