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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

UniprotKB/SwissProt ID: RPN1_MOUSE (Q91YQ5)

Gene Name: Rpn1

Organism: Mus musculus (Mouse).

Function: Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome (By similarity).

Network with metabolic pathway:
Kegg map ID Pathway Link
map00510N-Glycan biosynthesis
map04141Protein processing in endoplasmic reticulum
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of RPN1_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1478PAAEARMKVA C ITEQVLTLVN   4.41%MC1322178444-
2478PAAEARMKVA C ITEQVLTLVN   4.41%MC1320837516in vivo
3546SRLKTEGSDL C DRVSEMQKLD   3.64%MC1122178444-
4546SRLKTEGSDL C DRVSEMQKLD   3.64%MC1120837516in vivo