UniprotKB/SwissProt ID: RU17_HUMAN (P08621)
Gene Name: SNRNP70
Synonyms: RNPU1Z, RPU1, SNRP70, U1AP1
Organism: Homo sapiens (Human).
Function: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus speckle (By similarity). Nucleus, nucleoplasm (By similarity). Note=Colocalizes with SCNM1 and LUC7L2 in nuclear speckles (By similarity).
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