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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Adenosylhomocysteinase 1

UniprotKB/SwissProt ID: SAHH1_ARATH (O23255)

Gene Name: SAHH1

Synonyms: EMB1395, HOG1

Organism: Arabidopsis thaliana (Mouse-ear cress).

Function: Adenosylhomocysteine is a competitive inhibitor of S- adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. Required for DNA methylation-dependent gene silencing.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR000043
IPR015878

The S-nitrosylation sites of SAHH1_ARATH

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1244TKSKFDNLYG C RHSLPDGLMR HHHHHCCCCC C HHHHHHHHHH 1.92%AC0315734904in vivo
in vitro
2244TKSKFDNLYG C RHSLPDGLMR HHHHHCCCCC C HHHHHHHHHH 1.92%AC0322115780-
3268VMIAGKVAVI C GYGDVGKGCA HHHCCCEEEE E ECCHHHHHHH 2.49%AC0315734904in vivo
in vitro
4268VMIAGKVAVI C GYGDVGKGCA HHHCCCEEEE E ECCHHHHHHH 2.49%AC0322115780-