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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: GTP-binding protein SAR1a

UniprotKB/SwissProt ID: SAR1A_MOUSE (P36536)

Gene Name: Sar1a

Synonyms: Sara, Sara1

Organism: Mus musculus (Mouse).

Function: Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum (By similarity). Golgi apparatus (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001806
IPR005225
IPR006687
IPR006689

The S-nitrosylation sites of SAR1A_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1178LNARPMEVFM C SVLKRQGYGE HCCCEEEEEE E EECCCCCHHH 1.40%MC1121278135in vitro