Protein Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
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UniprotKB/SwissProt ID: SDHA_HUMAN (P31040)
Gene Name: SDHA
Synonyms: SDH2, SDHF
Organism: Homo sapiens (Human).
Function: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | HPRD | 02914 | Leigh syndrome due to mitochondrial complex II deficiency | | HPRD | 02914 | Mitochondrial complex II deficiency |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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