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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Succinate dehydrogenase iron-sulfur subunit

UniprotKB/SwissProt ID: SDHB_ECOLI (P07014)

Gene Name: sdhB

Organism: Escherichia coli (strain K12).

Function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell inner membrane; Peripheral membrane protein.

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

3D Structure Databases:
3D structure databases
EntryMethodResolution (A)ChainPositionsView
1NEK X-ray 2.60 A B1-238Link
1NEN X-ray 2.90 A B1-238Link
2ACZ X-ray 3.10 A B1-238Link
2AD0 Model - B1-238Link
2WDQ X-ray 2.40 A B/F/J1-238Link
2WDR X-ray 3.20 A B/F/J1-238Link
2WDV X-ray 3.20 A B/F/J1-238Link
2WP9 X-ray 2.70 A B/F/J1-238Link
2WS3 X-ray 3.20 A B/F/J1-238Link
2WU2 X-ray 2.50 A B/F/J1-238Link
2WU5 X-ray 2.80 A B/F/J1-238Link

The S-nitrosylation sites of SDHB_ECOLI

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
175LNMNGKNGLA C ITPISALNQP   %EC0222178444-