Protein Name: Signal transducer and activator of transcription 5B
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UniprotKB/SwissProt ID: STA5B_HUMAN (P51692)
Gene Name: STAT5B
Organism: Homo sapiens (Human).
Function: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity). Nucleus (By similarity). Note=Translocated into the nucleus in response to phosphorylation (By similarity).
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Protein disease:
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| Disease database |
Database Entry |
Disease information | | HPRD | 05037 | Growth hormone insensitivity with immunodeficiency |
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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| Overview of Protein S-nitrosylation Sites with Functional and Structural Information |  |
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