Protein Name: Synaptic vesicle glycoprotein 2A
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UniprotKB/SwissProt ID: SV2A_MOUSE (Q9JIS5)
Gene Name: Sv2a
Synonyms: Kiaa0736, Sv2
Organism: Mus musculus (Mouse).
Function: Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. Receptor for the botulinium neurotoxin type A/BOTA.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein (By similarity). Note=Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic-like microvesicles
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Network with metabolic pathway:
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Graphical Visualization of S-nitrosylation Sites:
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Overview of Protein S-nitrosylation Sites with Functional and Structural Information | |
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