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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: T-complex protein 1 subunit alpha

UniprotKB/SwissProt ID: TCPA_MOUSE (P11983)

Gene Name: Tcp1

Synonyms: Cct1, Ccta

Organism: Mus musculus (Mouse).

Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information

The S-nitrosylation sites of TCPA_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1357QAEEVVQERI C DDELILIKNT   7.26%MC0920925432in vivo
2385IILRGANDFM C DEMERSLHDA   3.96%MC0124926564-
3397EMERSLHDAL C VVKRVLELKS   3.38%MC0124926564-
4397EMERSLHDAL C VVKRVLELKS   3.38%MC0120925432in vivo