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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: T-complex protein 1 subunit delta

UniprotKB/SwissProt ID: TCPD_MOUSE (P80315)

Gene Name: Cct4

Synonyms: Cctd

Organism: Mus musculus (Mouse).

Function: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Melanosome (By similarity). Cytoplasm, cytoskeleton, microtubule organizing center, centrosome (By similarity).

Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001844
IPR002194
IPR002423
IPR008950
IPR012717

The S-nitrosylation sites of TCPD_MOUSE

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
1252EKAKIGLIQF C LSAPKTDMDN CCCEEEEEEC C CCCCCCCCCC 1.36%MC0121278135in vitro
2379GSGKLFKITG C TSPGKTVTIV CCCHHHHHHH H HCCCCEEEEE 2.26%MC0120925432in vivo
3410EAERSIHDAL C VIRCLVKKRA HHHHHHHHHH H HHHHHHHCCC 2.28%MC0124926564-
4410EAERSIHDAL C VIRCLVKKRA HHHHHHHHHH H HHHHHHHCCC 2.28%MC0120925432in vivo
5410EAERSIHDAL C VIRCLVKKRA HHHHHHHHHH H HHHHHHHCCC 2.28%MC0121278135in vitro
6450SRTLSGMESY C VRAFADAMEV HCCCCHHHHH H HHHHHHHHHH 2.02%MC0624926564-