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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Thioredoxin-like protein 1

UniprotKB/SwissProt ID: TXNL1_HUMAN (O43396)

Gene Name: TXNL1

Synonyms: TRP32, TXL, TXNL

Organism: Homo sapiens (Human).

Function: Active thioredoxin with a redox potential of about -250 mV.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Note=At least 85% of the cellular TXNL1 is proteasome-associated.

PDB :
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Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR006662
IPR010400
IPR012335
IPR012336
IPR013766
IPR015467

The S-nitrosylation sites of TXNL1_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
134LAVVKFTMRG C GPCLRIAPAF EEEEEEECCC C CHHHHHHHHH 3.76%HC0323010496
(Cys32)
-
234LAVVKFTMRG C GPCLRIAPAF EEEEEEECCC C CHHHHHHHHH 3.76%HC0323796488
(Cys32)
-
337VKFTMRGCGP C LRIAPAFSSM EEEECCCCCH H HHHHHHHHHH 2.12%HC0523010496
(Cys35)
-
437VKFTMRGCGP C LRIAPAFSSM EEEECCCCCH H HHHHHHHHHH 2.12%HC0523796488
(Cys35)
-