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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Tricarboxylate transport protein, mitochondrial

UniprotKB/SwissProt ID: TXTP_HUMAN (P53007)

Gene Name: SLC25A1

Synonyms: SLC20A3

Organism: Homo sapiens (Human).

Function: Involved in citrate-H(+)/malate exchange. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein.

Protein disease:
Disease database Database Entry Disease information
OMIM190315SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER, CITRATE TRANSPORTER), MEMBER 1; SLC25A1 ;;S
OMIM615182COMBINED D-2- AND L-2-HYDROXYGLUTARIC ACIDURIA; D2L2AD
Graphical Visualization of S-nitrosylation Sites:
Overview of Protein S-nitrosylation Sites with Functional and Structural Information
InterPro ID Domain
IPR001993
IPR002067
IPR002113

The S-nitrosylation sites of TXTP_HUMAN

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site Substrate Motifs PubMed ID Experiment
170HPPRYRGIGD C VRQTVRSHGV CCCCCCCHHH H HHHHHHHCCC 1.98%HC0124105792-